Role Title: Research intern, Public Data Collection: Neutrophil Gene Expression
Organisation: Telethon Kids Institute
Internship Period: Summer (November - December)
The intern will be joining the Neutrophils in Early Respiratory Disease team at Telethon Kids Institute led by Dr Luke Garratt, who has a new project with Dr Emma de Jong to investigate neutrophil gene expression data for treatments to mitigate chronic neutrophil activity.
The main project that the intern will be assisting with is to review the literature on neutrophil gene expression across health and disease, prioritising publications featuring microarray, RNAseq and/or single cell studies. The intern will go through these manuscripts for details regarding methodology and sample origins, and identify publicly available resources, such as data uploaded to the Gene Expression Omnibus (GEO). It is expected that a central resource containing this information is created for future reference by the group and where possible, retrieve GEO and other resources relating to Cystic Fibrosis and/or airway neutrophils onto Institute servers for preliminary analysis. The intern may also be able to participate in laboratory work generating novel RNAseq data if induction requirements are met. This project will be well-suited to an intern who has an active interest in computational biology, the immune system, and an opportunity to contribute to team publications. The intern will work closely with other honours and Ph.D. level students, in addition to post-doctoral and senior staff at the Institute.
The Telethon Kids Institute is based within the Perth Children’s Hospital, and is one of the largest, and most successful medical research institutes in Australia, comprising a dedicated and diverse team of around 1,000 staff, students and honoraries. We've created a bold blueprint that brings together community, researchers, practitioners, policy makers and funders, who share our vision to improve the health and wellbeing of children through excellence in research.